Cutaneous Lymphomas — Part II: Other Cutaneous Lymphomas

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Primary cutaneous lymphomas.

Primary cutaneous lymphomas have a distinct clinical behavior and prognosis, and therefore require a different therapeutic approach, as compared with their primary nodal equivalents. The European Organization for Research and Treatment of Cancer (EORTC) classification for primary cutaneous lymphomas recognizes a limited number of cutaneous T-cell lymphomas and cutaneous B-cell lymphomas and is ...

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Clinical features and history Cutaneous B-cell lymphomas usually present as one or more erythematous papules or nodules that may coalesce to form plaques. They are usually localized tumors effecting one cutaneous region and rarely ulcerate. There is some regional predilection for various sub-types of tumors; follicle center lymphoma more commonly arises on the scalp, marginal zone B-cell lympho...

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Cutaneous lymphomas are a heterogeneous group of lymphoproliferative disorders. Most of the cutaneous lymphomas present a rather good prognosis because they disseminate to internal organs late in the disease process, if at all. Since radiotherapy and intensive chemotherapy have limited efficacy, immunological interventions are regularly used in this disease group. These interventions include un...

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Primary cutaneous T-cell lymphomas.

Primary cutaneous T-cell lymphomas (CTCLs) encompass a clinically and biologically heterogeneous group of non-Hodgkin lymphomas (NHLs) defined by clonal proliferation of skin-homing malignant T lymphocytes and natural killer cells. They account for up to 75% to 80% of all cutaneous lymphomas. The current WHO-EORTC classification of cutaneous lymphomas with primary cutaneous manifestations lists...

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The Immunologic and Clinicopathologic Heterogeneity of Cutaneous Lymphomas Other Than

Twenty-one cases of non-Hodgkin s lymphoma with cutaneous involvement, other than mycosis fungoides, were evaluated immunologically, histologically, and clinically. Ten patients presented with skin disease alone, seven with concurrent cutaneous and extracutaneous disease, and four with extracutaneous disease only. Twenty of the 21 cases were nonepidermotropic tumors and were equally likely to e...

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ژورنال

عنوان ژورنال: Actas Dermo-Sifiliográficas (English Edition)

سال: 2021

ISSN: 1578-2190

DOI: 10.1016/j.adengl.2020.12.008